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Background Childhood-onset psoriasis (COP), a distinct clinical entity, may be associated with HLA-Cw6 positivity and metabolic and cardiovascular complications. There is some evidence that HLA-Cw6 positivity is associated with more extensive or severe...

In the FUTURE 2 study, secukinumab demonstrated rapid onset of action, was significantly superior to placebo in improving signs and symptoms of psoriatic arthritis (PsA), with efficacy sustained over one year[1] Secukinumab is the first IL-17A inhibitor...

Other Names: Arthritis psoriatica,Arthropathic psoriasis or Psoriatic arthropathy Definition: Psoriatic arthritis is a form of arthritis that affects some people who have psoriasis — a condition that features red patches of skin topped with silvery...

Introduction. Psoriasis is a T cell-mediated inflammatory disease in which pathogenesis T helper (Th) lymphocytes (Th1, Th17, and Th22) play an important role. The aim of the study was to assess the serum levels of some cytokines involved in the Th1...

Ever wondered what we would become like if our immune system gets out of order. Well this happens in many cases that the immune system which is guided to kill foreign bodies, starts acting against the very own cells of the body. The immune cells might...